Acetyl Hexapeptide-3
Synthetic hexapeptide that mimics the SNAP-25 protein targeted by botulinum toxin. Argireline reduces wrinkle formation by inhibiting neurotransmitter release at the neuromuscular junction, providing a topical "Botox-like" effect.
Mimics N-terminal of SNAP-25, competing with SNARE complex formation. Inhibits vesicle fusion and neurotransmitter release at motor endplates. Reduces muscle contraction intensity. Decreases expression of MMPs that degrade collagen. Promotes fibroblast proliferation.
Topical: 5-10% concentration in serum/cream twice daily.
Argireline: topical botulinum-like peptide
Acetyl hexapeptide-3 in wrinkle reduction
Topical peptides vs botox: comparative review
Room temperature. Protect from light.