Proapoptotic Peptide
Proapoptotic peptide selectively destroying white adipose tissue by inducing apoptosis in fat blood vessels. Dramatic weight loss in preclinical studies. Still experimental.
Binds prohibitin on adipose vasculature. Delivers proapoptotic sequence to fat blood vessel endothelium. Induces apoptosis → ischemia → adipocyte death. Selective for white fat.
Research: 50-200 mcg/kg daily. Human dosing not established.
Adipotide targeted destruction of white fat
Proapoptotic peptides in obesity
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